This absence of data creates a knowledge gap regarding the safety of microdosing for nursing mothers. Keep in mind that infants are particularly vulnerable to any substances consumed by the breastfeeding parent. Given the potential risks and lack of evidence supporting the safety of psychedelics during this period, it is prudent for breastfeeding individuals to avoid microdosing. “However, these types of studies take time, money and rigor—and don’t always pan out,” he said. Mental Health BenefitsMicrodosing is gaining recognition as a tool for managing mental health. Many users report reduced symptoms of depression and anxiety, attributing this to the way psychedelics encourage introspection and Substance abuse emotional processing.

You’re in!
With an intentional approach, microdosing can open the door to new perspectives and possibilities. As research continues to shed light on its effects, this practice has the potential to transform how we approach mental health, productivity, and self-discovery. Determining the Right DoseA microdose is typically about 1/10th of a full dose, but the exact amount depends on the substance and individual sensitivity. For psilocybin, this usually ranges from 0.1 to 0.3 grams of dried mushrooms. Choosing the Right SubstanceThe first step in microdosing is selecting the right substance.
Possible Benefits of Microdosing
- We can also connect you with experienced microdosing coaches who can provide personalized guidance, feedback, and mentoring to help you reach your goals and set you up for lasting success.
- While the social landscape surrounding drug use is seeing some small shifts, this is a big roadblock to more clinical trials being conducted on microdosing.
- Most people who microdose take about 10% of the standard psychoactive dose and use them over long periods of time rather than just once.
- It is critical to pay attention to the legality and the quality of your product — you likely can’t afford to get into legal jeopardy, and certainly can’t afford to poison yourself.
Plus, frequent piercing of compounded GLP-1 vials, if not done carefully, can also introduce bacteria into the medication and potentially contaminate it. “For a GLP-1 agonist such as a semaglutide like Ozempic, the What is microdosing lowest dose for starting is usually 0.25 milligrams weekly,” says Richard Siegel, MD, codirector of the Diabetes and Lipid Center at Tufts Medical Center. I really don’t feel comfortable offering any advice here as I’m not a medical professional.
Full Guide: Psychedelic Medicine 101

When ingested, psilocybin is metabolized into psilocin, which interacts with serotonin receptors in the brain to produce altered states of consciousness and perception. If you’re considering microdosing psilocybin, talking with a doctor or therapist about whether microdosing or psychedelic therapy may be right for you can be a good starting point. Addy notes that possessing and using psilocybin mushrooms in the United States is illegal (yes, even in Oregon where it’s recently been decriminalized). “On the ‘off days’ — day 2 and 3 when you aren’t taking a microdose, you might feel more focused and productive,” he adds. Microdosing describes using a psychoactive substance at a dose lower than what’s needed for recreational use.
